Tuesday, February 7, 2023

Pediatric Seminoma

Background

Testicular tumors in children are rare, accounting for only 1-2% of all solid tumors in this age group.
 The annual incidence of testicular tumors in children is 0.5 to 2.0 per 100.000, with the majority occurring in less than two years of age.
In both children and adults, the vast majority of testis tumors arise from germ cells. Seminoma is a type of testicular germ cell tumor that is believed to originate from the germinal epithelium of the seminiferous tubules. These tumors have been shown to have dramatic sensitivity to both radiotherapy and cytotoxic chemotherapy. In most patients with testicular tumors (including seminoma), the disease is readily cured with minimal long-term morbidity. The management of childhood seminoma is similar to that of adult seminoma.

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