Background
Infections due to Salmonella species represent a major public health problem in many countries. In the United States, nontyphoidal Salmonella (NTS) is the most common pathogen implicated in food-borne gastroenteritis.
In most cases, NTS is a self-limiting disease that causes mild gastroenteritis; however, it can lead to a wide spectrum of complications including bacteremia, enterocolitis, and severe local infections such as meningitis and osteomyelitis.
Salmonella serotype typhi can cause serious and prolonged bacteremic illness referred to as enteric fever or typhoid fever.