Monday, February 26, 2024

Abnormal Labor


To define abnormal labor, a definition of normal labor must be understood and accepted. Normal labor is defined as uterine contractions that result in progressive dilation and effacement of the cervix. By following thousands of labors resulting in uncomplicated vaginal deliveries, time limits and progress milestones have been identified that define normal labor. Failure to meet these milestones defines abnormal labor, which suggests an increased risk of an unfavorable outcome. Thus, abnormal labor alerts the obstetrician to consider alternative methods for a successful delivery that minimize risks to both the mother and the infant.

Dystocia of labor is defined as difficult labor or abnormally slow progress of labor. Other terms that are often used interchangeably with dystocia are dysfunctional labor, failure to progress (lack of progressive cervical dilatation or lack of descent), and cephalopelvic disproportion (CPD).

Friedman’s original research in 1955 defined the following three stages of labor

The first stage starts with uterine contractions leading to complete cervical dilation and is divided into latent and active phases. In the latent phase, irregular uterine contractions occur with slow and gradual cervical effacement and dilation. The active phase is demonstrated by an increased rate of cervical dilation and fetal descent. The active phase usually starts at 3-4 cm cervical dilation and is subdivided into the acceleration, maximum slope, and deceleration phases.

The second stage of labor is defined as complete dilation of the cervix to the delivery of the infant.

The third stage of labor involves delivery of the placenta.

See images below for the normal labor curves of both nulliparas and multiparas. The following table shows abnormal labor indicators.

Labor curve for nulliparas.

Labor curve for nulliparas.

View Media Gallery

Labor curve for nulliparas versus multiparas.

Labor curve for nulliparas versus multiparas.

View Media Gallery

Table. Abnormal Labor Indicators (Open Table in a new window)




Prolonged latent phase

>20 h

>14 h

Average second stage

50 min

20 min

Prolonged second stage without (with) epidural

>2 h (>3 h)

>1 h (>2 h)

Protracted dilation

< 1.2 cm/h

< 1.5 cm/h

Protracted descent

< 1 cm/h

< 2 cm/h

Arrest of dilation*

>2 h

>2 h

Arrest of descent*

>2 h

>1 h

Prolonged third stage

>30 min

>30 min

*Adequate contractions >200 Montevideo units [MVU] per 10 minutes for 2 hours. (Please refer to the Pathophysiology for information regarding adequate contractions.)


Abnormal labor constitutes any findings that fall outside the accepted normal labor curve. However, the authors hesitate to apply the diagnosis of abnormal labor during the latent phase because it is easy to confuse prodromal contractions for latent labor. In addition, the original labor curve, as defined by Friedman, may not be completely applicable today.

Contemporary practice with supporting data suggest that the duration of labor appears longer today than in the past. For both nulliparous and multiparous women, labor may take longer than 6 hours to progress from 4 cm to 5 cm and longer than 3 hours to progress from 5 cm to 6 cm of dilation. Cervical dilation of 6 cm appears to be a better landmark for the start of the active phase. The 95th percentile for duration of the second stage in a nulliparous woman with conduction anesthesia is closer to 4 hours.
Note the charts below.

Average labor curves by parity in singleton term p

Average labor curves by parity in singleton term pregnancies with spontaneous onset of labor. Reprinted from Seminars in Perinatology, Vol 36(5), El-Sayed YY, Diagnosis and Management of Arrest Disorders: Duration to Wait, pgs 374-8, Oct 2012, with permission from Elsevier.

View Media Gallery

The 95th percentiles of cumulative duration of lab

The 95th percentiles of cumulative duration of labor from admission among singleton term nulliparous women with spontaneous onset of labor, vaginal delivery, and normal neonatal outcomes. Reprinted from Seminars in Perinatology, Vol 36(5), El-Sayed YY, Diagnosis and Management of Arrest Disorders: Duration to Wait, pgs 374-8, Oct 2012, with permission from Elsevier.

View Media Gallery

First stage of labor

As stated above, first stage of labor is divided into latent and active phases. According to Friedman et al., latent stage considered to be prolonged if takes >20 hours for nulliparous women and >14 hours for multiparous women. However, prolonged latent phase does not usually lead to any clinically significant adverse events for mother or the infant. Therefore, diagnosis of abnormal labor during the latent phase is uncommon and is not relevant for clinical practice.

Around the time uterine contractions cause the cervix to become 3-4 cm dilated, the patient usually enters the active phase of the first stage of labor, according to the traditional definition. Abnormalities of cervical dilation (protracted dilation and arrest of dilation) as well as descent abnormalities (protracted descent and arrest of descent) as described historically are outlined in the Table above.

Both American College of Obstetrics and Gynecology (ACOG) and the Consortium on Safe Labor have proposed extending the minimum period before diagnosing active-phase arrest. The Consortium on Safe Labor defines 6 hours as the 95th percentile of time to go from 4 cm to 5 cm dilation, with the active phase defined as beginning at 6 cm (instead of 4 cm). According to this study, the 95th percentile of rate of dilation in active phase is 0.5 cm/hr to 0.7 cm/hr for nulliparous women and from 0.5 cm/h to 1.3cm/hr for multiparous women.
  ACOG has also stated that extending the time from 2 to 4 hours with oxytocin augmentation appears effective. Irrespective of the duration, maternal and fetal well-being status must be confirmed. In another study it was found that extending oxytocin augmentation for an additional 4 hours, up to 8 hours total, in patients who were dilated at least 3cm and had unsatisfactory progress resulted in a greater number of vaginal deliveries (38% delivered vaginally) without any evidence of fetal compromise.

According to the most recent evidence, arrest of labor in the first stage should be defined as more than or equal to 6cm dilation with ruptured membranes and one of the following: 4 hours or more of adequate contractions (>200 MVU) or 6 hours or more of inadequate contractions and no cervical change.

The maternal risk of a first stage greater than the 95th percentile (>30 h) is associated with a higher cesarean delivery rate (adjusted odds ratio [aOR]: 2.28) and chorioamnionitis (aOR: 1.58). The neonatal risk is associated with a higher incidence of neonatal ICU admissions in the absence of any other of the major morbidities (aOR: 1.53).
These results were again confirmed by another study, which established that prolonged first stage of labor lead to increased risks of a prolonged second stage, maternal fever, shoulder dystocia, and admission to a level 2-3 nursery

Second stage of labor

The Consortium on Safe Labor also addressed the 95th percentile for the second stage for nulliparous women; it was 2.8 hours (168 min) without regional anesthesia and 3.6 hours (216 min) with regional anesthesia. For multiparous women, the 95th percentiles for second-stage duration with and without regional anesthesia remained around 2 hours and 1 hour, respectively.
However, other studies demonstrate the risks of both maternal and perinatal adverse outcomes rising with increased duration of the second stage, particularly for durations longer than 3 hours in nulliparous women and 2 hours in multiparous women.
One study found that if nulliparous women delivered after prolonged second stage, they were twice as likely to have operative vaginal delivery, three times as likely to develop chorioamnionitis, have higher odds of having episiotomy and 3rd or 4th degree lacerations, and one day longer median hospital stay.
.Thus, careful clinical assessment of fetal and maternal well-being must be confirmed when extending the duration of the first and second stages of labor.

Third stage of labor

The third stage of labor is the time from delivery of the infant to placental delivery. Historically, the duration of a normal third stage of labor was defined as less than 30min. This threshold was established by the study conducted by Combs et al. in 1991, in which 75% of placentas were delivered by 10 minutes and maternal morbidity and mortality increased if the third stage was increased beyond 30 min. However, a recently published article by Frolova et al, puts this definition into a question. In this study, the researchers found that in a modern cohort, 90% of placentas are delivered within 10 minutes and the risk of postpartum hemorrhage almost doubles by the time the duration of third stage reaches twenty minutes.
 Therefore, the traditional definition of prolonged third stage being >30 min, may be outdated and in need of revision.


- Advertisment -

Most Popular