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Antimicrobial Susceptibility

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Antimicrobial susceptibility tests are used to determine which specific antibiotics a particular bacteria or fungus is sensitive to. Most often, this testing complements a Gram stain and culture, the results of which are obtained much sooner. Antimicrobial susceptibility tests can guide the physician in drug choice and dosage for difficult-to-treat infections.

Results are commonly reported as the minimal inhibitory concentration (MIC), which is the lowest concentration of drug that inhibits the growth of the organism. Reports typically contain a quantitative result in µg/mL and a qualitative interpretation. The interpretation usually categorizes each result as susceptible (S), intermediate (I), resistant (R), sensitive-dose dependent (SD), or no interpretation (NI).

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