Tuesday, February 7, 2023

Androstenedione

Reference Range

Androstenedione is a C-19 (19 carbon atoms) steroid hormone found in men as well as in premenopausal women. Androstenedione originates in the gonads, with minor contribution from the adrenal glands (1.5-3 mg/day); in postmenopausal women, the adrenal gland constitutes the major source of this hormone.

Androstenedione production in the adrenal glands is under effect of the adrenocorticotropic hormone (ATCH), whereas in the gonadal is controlled by the luteinizing hormone/follicle-stimulating hormone (LH/FSH). Each laboratory has its own reference range for androstenedione, depending on the assay. The table below shows the reference ranges.

Table 1. Androstenedione Reference Ranges (Open Table in a new window)

 

Conventional Units

SI Units

Men

 

 

18-30 y

50-220 ng/dL

175-768 nmol/L

31-50 y

40-190 ng/dL

140-663 nmol/L

51-60 y

50-220 ng/dL

175-768 nmol/L

Women

 

 

Follicular

35-250 ng/dL

122-873 nmol/L

Midcycle

60-285 ng/dL

209-995 nmol/L

Luteal

30-235 ng/dL

105-820 nmol/L

Postmenopausal

20-75 ng/dL

70-262 nmol/L

Children

 

 

1-12 mo

6-78 ng/dL

21-272 nmol/L

1-4 y

5-51 ng/dL

17-178 nmol/L

5-9 y

6-115 ng/dL

21-401 nmol/L

10-13 y

12-221 ng/dL

42-771 nmol/L

14-17 y

22-225 ng/dL

77-785 nmol/L

Tanner II-III

 

 

Male

17-82 ng/dL

59-286 nmol/L

Female

43-180 ng/dL

150-628 nmol/L

Tanner IV-V

 

 

Male

57-150 ng/dL

199-523 nmol/L

Female

7-68 ng/dL

24-237 nmol/L

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