Reference Range
As a major part of collagen, hydroxyproline has an essential role in collagen stability. Testing hydroxyproline in the serum and in the urine is common.
The reference range of hydroxyproline is as follows:
Total hydroxyproline in the urine among those aged 18-21 years – 13-28 mg/24/m2
Total hydroxyproline in the urine among those aged 22-55 years – 8.5-23.5 mg/24/m2
Free hydroxyproline in the serum of males – 0.7-1.55 µg/mL
Free hydroxyproline in the serum of females – 0.7-1.40 µg/mL