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Pathology of Pulmonary Infectious Granulomas

Definition

See the list below:

Granuloma – Focal collection of inflammatory cells at sites of tissue infection and includes activated macrophages (epithelioid cells), Langhans’ giant cells, and lymphocytes.

Caseation necrosis – Regions in granulomas with eosinophilic, granular, and friable (cheeselike) cellular debris with necrosis

Granulomatous inflammation – A distinctive pattern of chronic inflammatory reaction characterized by focal accumulation of activated macrophages (epithelioid histiocytes)

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