Specific Organisms and Therapeutic Regimens
Organism-specific therapeutic regimens for acute otitis media in adults are outlined below, including those for Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
Streptococcus pneumoniae
See the list below:
Amoxicillin 500 mg TID for 7-10d or
Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or
Cefuroxime 500 mg PO BID for 7-14d or
Cefpodoxime 200 mg PO BID for 7-10d or
Cefprozil 250-500 mg PO BID for 10d or
Ceftriaxone 1 g IM every other day for 3 doses or
Clindamycin 450 mg PO q6h for 10d
Haemophilus influenzae
See the list below:
Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or
Cefuroxime 500 mg PO BID for 7-14d or
Cefpodoxime 200 mg PO BID for 7-10d or
Cefprozil 250-500 mg PO BID for 10d or
Ceftriaxone 1 g IM every other day for 3 doses
Moraxella catarrhalis
See the list below:
Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or
Cefuroxime 500 mg PO BID for 7-14d or
Cefpodoxime 200 mg PO BID for 7-10d or
Cefprozil 250-500 mg PO BID for 10d or
Ceftriaxone 1 g IM every other day for 3 doses