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Symptomatic Generalized Epilepsy

Background

Symptomatic generalized epilepsy (SGE) encompasses a group of challenging epilepsy syndromes. As a group, SGE has 3 main features: (1) multiple seizure types, especially generalized tonic and atonic seizures; (2) brain dysfunction other than the seizures, in the intellectual domain (mental retardation or developmental delay) and in the motor domain (cerebral palsy); and (3) EEG evidence of diffuse brain abnormality.

The following are examples of epilepsy syndromes that are included in the category of SGE:

Early myoclonic encephalopathy

Early infantine epileptic encephalopathy with suppression bursts or Ohtahara syndrome

West syndrome

Epilepsy with myoclonic atonic seizures

Epilepsy with myoclonic absence

Lennox-Gastaut syndrome

Progressive myoclonic epilepsies

See the following Medscape Reference epilepsy topics for more information on these conditions:

Absence Seizures

Benign Childhood Epilepsy

Complex Partial Seizures

Epilepsy and Seizures

Juvenile Myoclonic Epilepsy

Lennox-Gastaut Syndrome

Myoclonic Epilepsy Beginning in Infancy or Early Childhood

Partial Epilepsies

Reflex Epilepsy

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