Overview
The pathologic assessment of radical prostatectomy, like any pathologic evaluation, is based on gross and histologic examination. Good fixation, orientation, and delineation of surgical margins are critical in achieving optimal results.
This article describes a method for tissue preparation of radical prostatectomy that allows the production of whole-mount sections and the collection of fresh tissues for research without the use of specialized equipment. Using this technique, the authors’ laboratory of 5 technicians can adequately process over 600 prostatectomies per year, admixed with an additional 5000 other surgical specimens.