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Cardiac Rhabdomyoma Pathology

Definition

Cardiac rhabdomyoma is the most common primary pediatric tumor of the heart and is considered to be a hamartoma of developing cardiac myocytes.
This tumor may demonstrate mild atypical histologic features, but it lacks the capacity for metastasis or invasion. Although the behavior of a cardiac rhabdomyoma is benign, the positioning within critical areas in the heart can lead to lethal arrhythmias and chamber obstruction. The natural history of cardiac rhabdomyomas is one of spontaneous regression.

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