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Uterus Adenofibroma/Adenosarcoma Pathology


Adenosarcoma is a biphasic neoplasm composed of malignant stroma and benign epithelium,
 whereas adenofibroma is a biphasic neoplasm composed of benign stroma and benign epithelium. Adenofibromas are exceedingly rare, and there is a concern whether they truly exist or whether most cases are well-differentiated adenosarcomas.

See the image below.

Intraglandular polypoid projections characterize a

Intraglandular polypoid projections characterize adenofibroma/adenosarcoma at low power (hematoxylin and eosin stain, x200).

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