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Isolated Coronary Artery Anomalies

Background

The term coronary artery anomaly refers to a wide range of congenital abnormalities involving the origin, course, and structure of epicardial coronary arteries. By definition, these abnormalities occur in less than 1% of the general population.
Coronary artery anomalies are frequently found in association with other major congenital cardiac defects. This article, however, is focused on isolated coronary artery anomalies (ie, in the absence of other major congenital cardiac defects). In adults, the clinical interest in coronary anomalies relates to their occasional association with sudden death, myocardial ischemia, congestive heart failure, or endocarditis. In addition, presence of coronary artery anomalies may, at times, create challenges during coronary angiography, percutaneous coronary interventions, and coronary artery surgery.

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