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Primary Angiitis of the CNS

Practice Essentials

Primary angiitis of the central nervous system (PACNS) is frequently considered in the differential diagnosis in patients with cryptogenic neurologic illness or in young subjects with ischemic stroke. The absence of characteristic clinical, laboratory, or radiographic features of this rare disease make the diagnosis very difficult, and has contaminated the literature with unproven cases in which alternative diagnoses are plausible.

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