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HomeDermatologyAtrophia Maculosa Varioliformis Cutis

Atrophia Maculosa Varioliformis Cutis


Atrophia maculosa varioliformis cutis (AMVC) is a rare disease that presents as spontaneously formed facial scars in young adults. In 1918, Heidingsfeld
coined the disease name to describe the numerous spontaneously formed scars on the cheeks of a 20-year-old man.

Most commonly located on the cheeks, the scars vary in shape and size, resembling those from smallpox. A slight erythema or pruritus precedes the appearance of the scars by 1-2 days. The number of reports on this eruption in literature is limited, and even fewer are documented with skin biopsy specimens. Its etiology remains unknown, but elastic tissue pathology has been reported in histology findings.

Pedigree analysis suggests that AMVC is of autosomal dominant inheritance.

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