Wednesday, June 12, 2024

Pediatric Organophosphates Toxicity

Practice Essentials

Organophosphates and carbamates are the most frequently used insecticides worldwide. These compounds cause 80% of the reported toxic exposures to insecticides. Organophosphates produce a clinical syndrome that can be effectively treated if recognized early. The typically described muscarinic clinical syndrome in adults often does not occur in young children, who instead are more likely to present with altered levels of consciousness (see Presentation).
Severe exposures require expeditious anticholinergic therapy (see Treatment and Medication).

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